In ACC meetings in 2016, Professor kshipra Hemal introduced PROMISE, the study researched 10,003 men and women, including low, middle and high-risk and stable patients with coronary heart disease. Results showed that female patients had more cardiovascular risk factors, but many of them are low risk factors. In addition, depression, sedentary lifestyle, and family history of premature cardiovascular disease were common factors in female patients. The study also found that both men and women had common symptoms of chest pain and breathing difficulty.

Professor Hemal commented that the study suggested that gender factors should be taken into account in the diagnosis of cardiovascular disease, and the next step should be the study of the effect of gender on the prognosis of cardiovascular disease. The other study, led by Professor Noel Bairey Merz C., showed that many women pay high attention to cardiovascular risk factors, but only a small number of risk factors are confirmed by rigorous studies.

In the study of 1011 women aged 25 to 60, 74% were found to have at least one risk factor, and only 16% were told that they had cardiovascular risk factors. But 76% of them did not discuss cardiovascular problems with their friends or family. 34% were told to lose weight and 45% said they had to follow up health clinics before losing weight. Professor Noel Bairey Mer C. said that discrimination on weight was likely to be the main cause of women's reluctance to discuss heart health, and he called on the society to pay attention to weight and heart health.

A research launched by Edina Cenko showed women treatment and prognosis had differences with male patients, primary PCI delayed more than 2 hours in female patients are more common and short-term mortality of female significantly increased than that of male patients. Study included 6679 patients who underwent ST segment elevation myocardial infarction (STEMI) of PCI within 24 hours at the onset, and the study proved that the death risk was lower to have PCI within 2 hours. But for women, it is more common to have more than 2 hours of delay.