Coronary
heart disease is the number one killer of human, the common treatment is
percutaneous coronary intervention, implanting metal stents, to expand the
coronary lumen, restore myocardial blood flow.
But there’s still
a risk of restenosis of implanting metal stents, and drug coated stents can continue
to release drugs to prevent restenosis. However, the emergence of bio
absorbable stents provides more treatment for patients with coronary heart
disease.
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On July 5, 2016,
the FDA approved the first clinical application of fully absorbable stents in coronary
artery disease, named Absorb GT1 BVS. Its outside coating can release
everolimus to prevent restenosis, which will be slowly absorbed after about 3
years by human body.
The material of BVS
is man-made biodegradable polymer, similar to materials of absorption line and other
implantable medical device. BVS can be slowly degraded in the human body, and
finally remains 4 tube wall platinum markers to identify the location of the
stent placement.
As the accordance
approved, ABSORB III research included 2008 patients, compared the impact on
incidence of major adverse cardiac events of BVS and traditional drug coated
stents, the one year follow-up results of the study showed the incidence of BVS
group of major adverse cardiac events and thrombosis formation rate were
slightly higher than that of the conventional stent group.
Of course, there
are contraindications of BVS. It includes everolimus or scaffold materials such
as polymers and perkin allergy, and it is not suitable to do angioplasty, the
contrast agent allergy etc.
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